There are several ways to keep your computer more responsive while Kommodo is thinking:

 

•        Run the engine at “Lower than normal” priority. Most chess GUI will provide this option, for example:  Fritz/ChessBase has a "Priority Below Normal" checkbox in the dialog for creating the UCI engine.
 

•        If you want to use your computer for other purposes while analyzing chess positions, set the "Threads" configuration option to a value smaller than the the number of physical cores of your computer - for example, use 3 on a quad-core computer. This will leave one core available for other applications while the chess analysis runs in the background.